Intensive care

Vitamin D Binding Protein (VDBP) significantly varies in acute stress due to rapid fluid shifts. This variation leads to a significant change in the free 25OH Vitamin D concentration, at constant total 25OH Vitamin D levels. Therefore several research groups have studied the importance of free 25OH Vitamin D during acute stress.

  • QURAISHI S.A. (2012)

Vitamin D in acute stress and critical illness.

Curr. Opin. Clin. Nutr. Metab. Care, 15(6):625-34.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751798/

  • DE PASCALE G. (2014)

Vitamin D status in critically ill patients: the evidence is now bioavailable!

Critical Care, 18:449.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095727/

  • MADDEN K. (2015)

Critically Ill Children Have Low Vitamin D–Binding Protein, Influencing Bioavailability of Vitamin D.

Annals of the American Thoracic Society, Vol. 12, No. 11 (2015), pp. 1654-1661.

https://www.ncbi.nlm.nih.gov/pubmed/26356094